Recently, the therapeutic potential of magic mushrooms, particularly in addressing mental health disorders like depression, has sparked intrigue. An emerging trend involves the regular intake of around 25 mg of the active ingredient, available for purchase from a mushroom dispensary. This dosage has demonstrated potential as an effective adjunct to conventional depression treatments.
A scholarly study indicates that psilocybin, the active component in magic mushrooms, holds promising results in the treatment of depression.
Key Points:
- Psilocybin may reduce symptoms of depression in just eight days.
- The side effects of psilocybin are typically mild to moderate and are generally well-tolerated.
- A 25mg dose of psilocybin can lead to altered perception, mood changes, increased creativity, and a sense of unity.
A Single Dose May Be Sufficient
A recent study, designed with a rigorous, randomized, multi-blinded approach, compared a single dose of psilocybin with an active placebo (niacin). The study evaluated the onset, duration of benefits, and safety profile of psilocybin over a six-week span.
Study Participants
The study involved individuals aged 21 to 65 who met the criteria for Major Depressive Disorder (MDD) as defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders). These individuals were going through a depressive episode that had lasted at least 60 days at the time of the study.
Study Procedure
Participants received either a single 25-mg oral dose of psilocybin or a 100-mg dose of niacin. Niacin served as an active placebo, causing a swift physiological response (flushing) designed to maintain the blinding integrity.
Both the psilocybin and the niacin placebo were administered following a standard “set and setting” process. The preparatory sessions, conducted with two facilitators, lasted between 6 and
The dosing procedure took place in a relaxing environment, lasting between 7 to 10 hours. Participants were prompted to reflect upon their experiences four hours after the dosage was given.
Findings from the Study
Just eight days after the psilocybin was administered, a significant decrease in depressive symptoms was detected. This promising outcome sustained throughout the six-week check-in period. The results showed improved response and remission rates based on the Montgomery-Asberg Depression Rating Scale (MADRS), which were higher compared to other psilocybin studies and Treatment-Resistant Depression.
When compared to niacin, psilocybin displayed enhanced psychosocial functioning. The use of psilocybin showed potential benefits in a number of areas, including reducing overall disease severity, anxiety, self-reported depressive symptoms, and improving quality of life.
Most participants tolerated the substance well, experiencing only minor to moderate side effects, mainly with the first dose. However, compared to niacin, psilocybin treatment resulted in more frequent and severe side effects, which is consistent with our current understanding of its effects.
The researchers noted that psychedelics like psilocybin could cause side effects that standard rating scales may not always pick up, or could reveal previously undetected psychiatric conditions, even while effectively treating specific disorders.
What Does a 25-mg Dose Mean?
A standard psychedelic dosage varies from 15 to 25 milligrams of psilocybin (1.5 to 2.5 grams of dried mushrooms). This is the usual dosage for individuals looking for the full psychedelic effects of magic mushrooms.
This dosage can result in altered perception, mood shifts, enhanced creativity, and a feeling of unity with the environment. Mild visual effects might be experienced, but severe hallucinations are rare. It is akin to entering a vivid dreamlike state where reality blends seamlessly with an intriguing mix of visual and auditory sensations.
The euphoric feelings often express themselves through dance, subtle movements, or simply succumbing to the psychedelic rhythm. The experience usually lasts between 4 to 8 hours. At this level, visual distortions might become more pronounced. Patterns appear to move and morph, and the surroundings seem to pulsate with energy.
This dosage level can be managed, but it necessitates a controlled environment and a positive mindset. It offers a journey full of wonder and awe, encouraging exploration of consciousness. with a sense of excited caution.
- Enhanced color perception.
- Vision alterations, such as the sensation of objects moving or “breathing”.
- Synesthesia, a condition where one can “see sounds” or experience “auditory perceptions of colors”.
- A deeper comprehension of music.
- Bursts of laughter.
- Alterations in tactile sensations.
- Engagement in introspection.
- Euphoria.
- Changes in time perception.
- Increase in heart rate and blood pressure.
Products Offered at Magic Mushroom Stores
Magic mushroom stores offer an array of products laced with psilocybin. These include dried mushrooms, edibles, capsules, beverages, and more. Dried mushrooms are particularly well-liked.
Health Canada recognizes over 200 varieties of magic mushrooms, with Psilocybe cubensis being a popular choice. This strain comes in numerous variants, offering customers a vast selection similar to that found in cannabis dispensaries.
Other Shroom Products:
| Edibles | These include food items like gummies and chocolates infused with psilocybin. The dosage is easily manageable as manufacturers indicate the amount per serving. |
| Capsules | They are tasteless and can be seamlessly incorporated into your health routine. They contain only small doses to subtly enhance your day-to-day life. |
| Beverages | These are similar to edibles but in liquid form. They offer variety and can be found as chocolate, coffee, or tea. |
Choosing Your Dose at Magic Mushroom Dispensaries
Though magic mushrooms are not a typical treatment for depression, Canada has taken a progressive step by allowing the testing and medical use of psilocybin, a Schedule I substance under the Controlled Drugs and Substances Act, for patients suffering from severe major depressive disorder. This decision could potentially benefit tens of thousands who are experiencing symptoms of depression and anxiety, they may find different treatment options through clinical trials.
Commonly Asked Questions
What can I expect from a medicinal mushroom dispensary?
A medicinal mushroom dispensary usually offers products like Reishi, Turkey Tail, and Lion’s Mane. If you’re curious about the mushroom world, an online magic mushroom dispensary might be your ideal destination. These dispensaries offer a range of mushroom products, including dried mushrooms and various psychedelic substances.
Is a 25 mg dosage effective for depression treatment?
Research continues into the appropriate psilocybin dosage for treating depression. Some studies have considered lower dosages, while others have examined higher amounts of psilocybin. One possible approach could be starting with a microdose and gradually increasing the dosage.
Can I buy shrooms in Toronto?
Online mushroom suppliers offer the convenience of shopping from anywhere in Canada. Regardless of your province or city, these online services assure delivery right to your doorstep.
What’s the least expensive product in an online mushroom shop?
Dried mushrooms are typically the first choice for consumers due to the variety of quantities on offer. The price can fluctuate based on whether you require a small amount like 1 gram or plan to purchase in bulk. While edibles and other products have reasonable prices, they may not be as budget-friendly as dried mushrooms.
Can a single dose of shrooms help alleviate depression?
Some studies indicate that one use might be enough to lessen symptoms of depression. However, it’s important to remember that study participants also engaged in talk therapy alongside the treatment. The combination of psychedelic therapy and therapeutic sessions appears to yield the best results.
About the Author
This article was written by Charles L. Raison et al.; Jeremy D. Coplan, MD and Dorothy P. Reddy, MD; Albert Garcia-Romeu, Frederick S Barrett, Theresa M Carbonaro, Matthew W Johnson, and Roland R Griffiths; Vince Polito
Richard J. Stevenson, Rebecca Smausz, Joanna Neill, and John Gigg are also part of the team.
Affiliated Institutions:
- Usona Institute, based in Fitchburg, Wisconsin
- SUNY Downstate Medical Center in Brooklyn, New York
- Neurogenesis Clinics, located in Brooklyn, New York
- Johns Hopkins University School of Medicine’s Department of Psychiatry and Behavioral Sciences, Baltimore, MD, USA
- Johns Hopkins University School of Medicine’s Center for Psychedelic and Consciousness Research, Baltimore, MD, USA
- Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Johns Hopkins University School of Medicine’s Department of Psychiatry and Behavioral Sciences, Baltimore, USA
- Macquarie University’s Department of Cognitive Science, Sydney, Australia
- Department of Psychology at Macquarie University, Sydney, Australia
- The University of Manchester’s Division of Neuroscience and Experimental Psychology, within the Faculty of Biology, Medicine and Health, Manchester, UK
- Division of Pharmacy and Optometry at The University of Manchester, within the Faculty of Biology, Medicine and Health, Manchester, UK
- Medical Psychedelics Working Group, associated with Drug Science, UK
